The principal cytochrome P450 isoenzyme associated appears being CYP2E1, with CYP1A2 and CYP3A4 as additional pathways. Roughly 85% of the oral dose seems during the urine within 24 hours of administration, most since the glucuronide conjugate, with small amounts of other conjugates and unchanged drug.Just after halting utilization of a CYP2D6 inhi